Progress and Promise of Nur77-based Therapeutics for Central

nuri77The mechanism of Nur77 regulating cell survival and apoptosis in CNS. Nur77 mediates cell apoptosis through caspase, endoplasmic reticulum stress, and mitochondrial autophagy, whileThe expression of nur77 gene and Nur77 are induced at 0–4 hr after 10 µM forskolin treatment in PC12 cells. (A) PC12 cells were treated with 10 μM forskolin.nur77